| Title: | RAPID-TIA - feasability study for an RCT for GPs initiating secondary preventative measures |
| Principal research question: | The aim of the RAPID-TIA pilot trial is to determine the feasibility of a randomised controlled trial and cost effectiveness analysis to ask: Should general practitioners and emergency doctors (“primary care physicians” [PCP]) initiate secondary preventative measures in addition to aspirin in people they see with suspected TIA or minor stroke at the time of referral to a specialist? |
| Methodology description: | Patients with a suspected TIA will be randomly assigned to usual care or usual care plus additional early initiation of secondary prevention drugs (a blood pressure lowering protocol, simvastatin 40mg and dipyridamole 200mg m/r bd). |
| Sample group description: | We will recruit 170 patients from 30 general practices and 3 emergency departments |
| Outcome measure description: | The primary outcome of the main study will be stroke at 90 days. This pilot study will be used to estimate key parameters that are needed to design the main study and to estimate accuracy of primary care diagnosis of TIA. |
| Project organisation | |
| Start date: | 1st October 2011 |
| End date: | 31st December 2012 |
| Contact person: | Dr Duncan Edwards |
| Contact Details: | Strangeways Research Laboratory Worts Causeway Cambridge Cambs CB1 8RN UK Telephone: (01223) 330309 Fax: E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it |
| Collaborative: | Dr Kate Fletcher RAPID-TIA study manager Primary Care Clinical Sciences School of Health & Population Sciences University of Birmingham Edgbaston Birmingham B15 2TT Tel: +44 (0)121 414 8582 Fax: +44 (0)121 414 3759 Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it |
| Funding information | |
| Funding Organisation: | NIHR Research for Patient Benefit |
| Funding Reference: | |
| Funding Amount: | £248,000 |
| References and Publications | |