Dr. Malgorzata (Gosia) Wilinska

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My field of research is modelling and simulation in physiology with the main focus on diabetes. Being a member of Diabetes Modelling Group I work on a number of research projects related to glucose control. Most of my current efforts are spent on the EC-funded CLINICIP project (Closed Loop INsulin Infusion for the Critically Ill Patients www.clinicip.org ) which aims to develop a closed loop system for the critically ill. During the course of this project I have developed metabolic simulator for the purpose of testing different glucose controllers and predicting the results of clinical trials. I also work on a number of experiment-driven mathematical models which aim to represent various physiological processes within the glucoregulatory system.

Recent Key Publications:

Chassin LJ, Wilinska ME , Hovorka R. Grading system to assess clinical performance of closed-loop glucose control. Diabetes Technol Ther. 2005; 7:72-82.

Wilinska ME , Chassin LJ, Schaller HC, Schaupp L, Pieber TR, Hovorka R. Insulin kinetics in type-I diabetes: continuous and bolus delivery of rapid acting insulin. IEEE Trans Biomed Eng 2005; 52:3-12.

Wilinska ME , Bodenlenz M, Chassin LJ, Schaller HC, Schaupp L, Pieber TR, Hovorka R. Interstitial glucose kinetics in subjects with type 1 diabetes under physiologic conditions. Metabolism 2004; 53:1484-91.

Chassin LJ, Wilinska ME , Hovorka R. Evaluation of glucose controllers in virtual environment: methodology and sample application. Artif Intell Med 2004; 32:171-81.

Hovorka R, Canonico V, Chassin LJ, Haueter U, Massi-Benedetti M, Orsini Federici M, Pieber TR, Schaller HC, Schaupp L, Vering T, Wilinska ME . Nonlinear model predictive control of glucose concentration in subjects with type 1 diabetes. Physiol Meas 2004; 25:905-20. 

Other publications in pubmed listed by the U.S. National Library of Medicine.

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