Department of Radiology

School of Clinical Medicine

Department of Radiology Staff

gallagher

Ferdia A. Gallagher

Academic Appointments

   

Position(s)

Status(s):

         

University

Cancer Research UK Clinician Scientist Fellow, University of Cambridge and
CRUK Cambridge Research Institute

Honorary
Contract

Honorary Consultant Radiologist, Addenbrooke's Hospital Research Fellow,
Gonville and Caius College

 

Visiting Researcher, CRUK, Cambridge Research Institute.

 

Visiting Researcher, Department of Biochemistry.

Specialty

Oncological Imaging

Molecular Imaging

   

Contact

Email: FA Gallagher

 

Tel.: + 44 (0)1223 (7)67062 or 404173  

Profile

Dr Ferdia Gallagher studied medicine as an undergraduate at the University of Cambridge before completing his clinical studies at the University of Oxford. He trained as a radiologist at Addenbrooke’s Hospital in Cambridge. In 2005, he was awarded a Cancer Research UK (CRUK) and Royal College of Radiologists (RCR) clinical research training fellowship to undertake a PhD in Molecular Imaging at the Department of Biochemistry in Cambridge. This work focused on a new form of imaging termed hyperpolarized carbon-13 MRI that allows carbon metabolism to be imaged non-invasively. He is currently a CRUK Clinician Scientist Fellow at the CRUK Cambridge Research Institute, an Honorary Consultant Radiologist in the Department of Radiology in the University of Cambridge and a Research Fellow at Gonville & Caius College, Cambridge. His main interest is in developing molecular imaging techniques for oncological radiology and how these can be translated into humans. The focus of this work is to develop new molecular biomarkers for the detection of cancer as well as methods to assess early response of tumours to treatment with chemotherapy.

Professional Education

Degree

Awarding Institution

Field of Study

Graduated

 
BM. BCh. University of Oxford. Medicine 1999  
MA. University of Cambridge.   2000  
MRCP. Royal College of Physicians. Medicine 2002  
FRCR. Royal College of Radiologists.   Radiology 2005  

Current Research

Oncological Imaging.
Molecular Imaging.
Hyperpolarised 13C - Imaging.
Magnetic Resonance Imaging.

Main Collaborators

Professor Kevin Brindle, CRUK Cambridge Research Institute.
Professor David Lomas, University of Cambridge.
Dr Mikko Kettunen, CRUK Cambridge Research Institute.
Dr Jan Henrik Ardenkjær-Larsen,GE Healthcare, Amersham.
Dr Damian Tyler & Dr Marie Schroeder, University of Oxford.
Dr Mathilde Lerche and colleagues, Imagnia, Malmö, Sweeden.

Last 5 Publications

Production of Hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a Marker of Cell Necrosis and Treatment Response in Tumors.

Gallagher FA, Kettunen MI, Hu DE, Jensen PR, in ‘t Zandt R, Karlsson M, Gisselsson A, Nelson SK, Witney TH, Bohndiek SE, Hansson G, Pietersen T, Lerche MH, Brindle KM

Proceedings of the National Academy of Sciences of the U S A. In press.

A Comparison Between Radiolabeled Fluorodeoxyglucose Uptake and Hyperpolarized 13C-Labeled Pyruvate Utilization as Methods for Detecting Tumor Response to Treatment.

Witney TH, Kettunen MI, Day SE, Hu DE, Neves AA, Gallagher FA, Fulton SM, Brindle KM.

Neoplasia. 2009 Jun;11(6):574-82.

Imaging pH in vivo using Hyperpolarized 13C-labeled Bicarbonate.

Gallagher FA, Kettunen MI, Day SE, Hu D-E, Ardenkjær-Larsen JH,in‘t Zandt R, Jensen PR, Karlsson M, Golman K, Lerche & Brindle KM.

Nature 2008 453;940-943. Cover Article.

13C Magnetic Resonance Spectroscopy Measurements of Glutaminase Activity in Human Hepatocellular Carcinoma Cells using Hyperpolarized 13C-labeled Glutamine.

Gallager FA. Kettunen MI, Day SE, Lerche M & Brindle KM.

Magnetic Resonance in Medicine 2008 60(2);253-7.

Detecting Tumor Response to Treatment using Hyperpolarized 13C Magnetic Resonance Imaging and Spectroscopy.

Day SE, Kettunen MI, Gallagher FA, Hu D, Lerche M, Wolber J, Golman K, Ardenkjaer-Larsen JH & Brindle KM.

Nature Medicine 2007 13(11);1382-7 & 13(12):1521.

Published Book(s)

Oxford Handbook of Emergencies in Clinical Radiology.

Graham RNJ & Gallagher FA. Editors .

Oxford University Press. 2009