Professor Luigi Aloj

I graduated from the Universitá Federico II Medical School (Napoli, ITALY) in 1990. I trained in Nuclear Medicine at the same University obtaining a Specialist Degree in 1994. From 1994 to 1998 I worked in the Nuclear Medicine Department of the National Institutes of Health, USA as a Visiting Fellow and Visiting Associate.  

My main research interests are novel applications of radiolabelled pharmaceuticals for the study and treatment of cancer with contributions spanning from basic preclinical radiopharmaceutical development and mechanistic studies to novel clinical applications in nuclear medicine diagnostics and therapy. 

I have teaching experience with medical students, nuclear medicine and diagnostic radiology specialty trainees, medical physics and biomedical sciences graduate programs as well as PhD supervisions in nuclear medicine and related fields. 

I have been working in Cambridge since 2016, initially as an NHS Nuclear Medicine Consultant and am now Professor of Nuclear Medicine in the University Department of Radiology. 

Current projects

Early phase/first in human PET imaging studies: 

1. Imaging High Grade Serous Ovarian Cancer with 89Zr labelled Oregovomab;
2. Imaging CD8 trafficking in head and neck cancers in response to immunotherapy using [89Zr] IAB22M2C;
3. Imaging cell death with [18F]C2am for early prediction of response to treatment of cancer;  

Commercial trials on radionuclide theranostics for cancer with agents targeting PSMA and Gastrin Releasing Peptide Receptors. 

Preclinical and basic science projects on novel radioligands for cancer applications for imaging and therapy.