Brian Tom

Professor Brian Tom

(he/him/his)
Principal investigator

MRC Biostatistics Unit

About Professor Brian Tom

I am a Group Leader at the MRC Biostatistics Unit. 

I have worked at the Unit since December 2001, firstly as a research statistician, and then becoming a Group Leader in 2017. Prior to this, I worked as a consulting statistician and project statistician within the University of Cambridge Department of Public Health and Primary Care’s Centre for Applied Medical Statistics (CAMS) (1997-2000) and Epidemiology for Policy Group (2000-2001) respectively. I currently lead the Precision Medicine theme at the Unit. Prior to this, I worked within Professor Vern Farewell’s programme for “Statistical Modelling: theory and applications” which delt with methods of statistical inference for challenging data structures. I collaborate with other senior scientists (present and former) in the Unit, in particular Professor Sheila Bird, Dr Daniela De Angelis, Professor Wally Gilks and Professor Carlo Berzuini.

I am also Director of Studies at the Unit.  

Research Interests

  • Causal Inference
  • Chronic Disease Epidemiology (in particular related to Inflammatory Arthritis)
  • Dynamic Graphical Modelling of Stochastic Processes
  • Efficiency
  • Modelling of Longitudinal and Correlated Data
  • Multi-state Models and Survival Data
  • Stratified Medicine

Publications

Showing 1 to 10 of 186 publications

Journal-article

Large-scale molecular endotype discovery in synovial fluid reveals osteoarthritis as a single biological continuum

Authors: TA Perry, Y Deng, PA Hulley, RA Maciewicz, J Mitchelmore, S Larsson, J Gogain, S Brachat, A Struglics, CT Appleton, S Kluzek, NK Arden, D Felson, L Bondi, M Kapoor, LS Lohmander, TJ Welting, DA Walsh, AM Valdes, L Jostins-Dean, FE Watt, BDM Tom, TL Vincent, TA Perry, Y Deng, PA Hulley, RM Maciewicz, S Kluzek, NK Arden, TL Vincent, V Batchelor, J Mackay-Alderson, G Brewer, B Marsden, AJ Price, M Goff, V Kumar, J Tey, T Szommer, J Mitchelmore, S Brachat, J Gasser, L Jennings, S Larsson, A Struglics, LS Lohmander, J Gogain, D Perry, A Mitchel, E Zepko, CT Appleton, TB Birmingham, JD Klapak, D Felson, L Bondi, BDM Tom, M Kapoor, R Gandhi, A Perruccio, YR Rampersaud, K Perry, TJ Welting, P Emans, T Boymans, L Jutten, M Caron, GVD Akker, DA Walsh, AM Valdes, M Doherty, V Georgopoulos, A Papadaki, A Williams, T Hardingham, S Kennedy, J Tambiah, D Galesso, N Giordan, W Ali

Published:

Journal: Nature Communications

DOI: 10.1038/s41467-026-71632-4

Journal-article

Development of methodology to support molecular endotype discovery from synovial fluid of individuals with knee osteoarthritis: The STEpUP OA consortium

Authors: Y Deng, TA Perry, P Hulley, RA Maciewicz, J Mitchelmore, D Perry, S Larsson, S Brachat, A Struglics, CT Appleton, S Kluzek, NK Arden, D Felson, B Marsden, BDM Tom, L Bondi, M Kapoor, V Batchelor, J Mackay-Alderson, V Kumar, LS Lohmander, TJ Welting, DA Walsh, AM Valdes, TL Vincent, FE Watt, L Jostins-Dean

Published:

Journal: PLOS ONE

DOI: 10.1371/journal.pone.0309677