Professor Thomas Jaki

A fast, flexible simulation framework for Bayesian adaptive designs -- the R package BATSS

Authors: D-L Couturier, R Puhr, S Heritier, T Jaki, EG Ryan

Published: 1 July, 2026

DOI: 10.48550/arxiv.2410.02050

An evaluation of designs for Phase I/IIa dose-finding studies in Tuberculosis.

Authors: A Serra, P Mozgunov, PP Phillips, T Jaki

Journal: Stat Methods Med Res

DOI: 10.1177/09622802261430905

Optimal Weighted Tests for Replication Studies and the 'Two-Trials Rule' With Multiple Hypotheses.

Authors: DS Robertson, T Jaki

Journal: Stat Med

DOI: 10.1002/sim.70638

Introducing precision-weighted bias as a performance measure to inform the inclusion of adaptive designs in meta-analysis

Authors: M Law, DS Robertson, SS Villar, TP Morris, B Choodari-Oskooei, T Jaki, IR White

Published: 10 June, 2026

DOI: 10.48550/arxiv.2606.12015

A randomized controlled Phase I de-escalation trial of molnupiravir and nirmatrelvir/ritonavir combination for mild-moderate SARS-CoV-2 infection.

Authors: SH Khoo, R FitzGerald, CJ Edwards, S Ahmad, G Saunders, LJ Else, V Shaw, P Mozgunov, J Northey, L Dickinson, E Knox, A Buadi, C Hale, HE Reynolds, C Middleton, K Bullock, L Walker, M Tetlow, R Lyon, J Gibney, A Amara, W Greenhalf, A Burdon, J Dixon, T Jaki, J Chiong, DG Lalloo, A Owen, M Jacobs, T Fletcher, G Griffiths, AGILE CST-8 study group

Published: 3 June, 2026

Journal: J Antimicrob Chemother

DOI: 10.1093/jac/dkag180

Optimal Dose and Safety of Intravenous Favipiravir in Hospitalized Patients With COVID-19: A Dose-Escalating, Randomized Controlled Phase Ib Study.

Authors: T Rowland, R FitzGerald, E Challenger, L Dickinson, LJ Else, L Walker, C Hale, V Shaw, C Kelly, R Lyon, J Gibney, K Dhamani, M Irwin, Y Enever, M Tetlow, W Wood, H Reynolds, J Chiong, O Osanlou, H Pertinez, K Bullock, W Greenhalf, A Owen, DG Lalloo, M Jacobs, JA Hiscox, T Jaki, P Mozgunov, G Saunders, G Griffiths, SH Khoo, TE Fletcher, AGILE CST‐6 Study Group

Journal: Clin Pharmacol Ther

DOI: 10.1002/cpt.70261

Extension and Application of the Partial Continual Reassessment Method to a Phase-IIa Dose-Finding Tuberculosis Trial with a Continuous Endpoint

Authors: A Serra, T Jaki, P Mozgunov

Published: 27 May, 2026

Journal: Statistics in Biopharmaceutical Research

DOI: 10.1080/19466315.2026.2676642

Operationalizing Allocation Probability Tests: Practical Guidance on Optimized Implementation for Power and Robustness

Authors: S Zetterstrom, DS Robertson, T Jaki, SS Villar

Published: 8 May, 2026

DOI: 10.48550/arxiv.2605.07620

Modern Clinical Trials: Seamless Designs and Master Protocols.

Authors: A Burdon, T Jaki, X Chen, P Mozgunov, H Zheng, R Baird

Journal: Cancer Med

DOI: 10.1002/cam4.71858

The RECOVERY Trial:

Authors: L Ding, T Jaki, J Ye

Published: 30 April, 2026

DOI: 10.1201/9781003424963-25