Cambridge Institute for Therapeutic Immunology and

CITIID scientists are studying human immunity across scale, from molecules and pathways within cells, to the whole patient in experimental medicine studies, generating insights that will help to change clinical outcomes. - Professor Menna Clatworthy, CITIID Director

Our experts work with NHS clinicians, industry, patients, and international research partners in Africa and Asia. We have state-of-the-art facilities to address important problems and find solutions that will improve patient outcomes and population health.

We have over 300 scientists within 25 research groups across 3 sites on the Cambridge Biomedical Campus:

Jeffrey Cheah Biomedical Centre (main base, incorporating the largest academic biosecure containment level 3 facility in the UK)
Molecular Immunity Unit, embedded within the MRC Laboratory of Molecular Biology
Addenbrooke Hospital - a number of laboratories, including additional CL3 capacity, embedded in CUH, housing a number of groups and supporting key experimental medicine platforms such as the Tissue Immunity Laboratory and Cambridge Human Organ Perfusion Facility.

You can study PhD in Immunity and Infection which will give you the opportunity to use a mix of capabilities in basic research and clinical facilities to tackle some of the biggest global health challenges.

We research immune-mediated diseases to understand:

genetic contributions to susceptibility
how different immune cells in blood and tissue contribute to disease
how microbes interact with host to avoid detection and resist the immune system

We use this information to:

accelerate diagnosis and treatment stratification
identify new therapeutic targets
unveil the mechanisms by which the microbiome influences systemic immunity

We have established collaborations with industry and with international research partners, and actively engage and involve our local community, both patients and the public.

Research themes

Our research themes are:

Immunity and autoimmune diseases
Infectious diseases – pathogenesis, host immune response and the microbiome.

Principal Investigators

Professor Arthur Kaser FMedSci
Dr Anneliese Speak
Dr Chris Wallace
Professor Christoph Hess
Professor Clare Bryant
Dr David Jayne
Professor David Thomas
Professor Eoin McKinney
Dr Ewan Harrison
Dr Felix Randow
Dr Florian Marks
Emeritus Professor Gordon Dougan
Professor James Nathan
Professor Lalita Ramakrishnan
Dr Mark Wills
Professor Matthew Cook
Professor Menna Clatworthy
Professor Michael Weekes
Dr Nicholas Matheson
Dr Nicole Kaneider
Professor Paul Lehner
Dr Paul Lyons
Professor Ravindra Gupta
Dr Richard Timms
Dr Rona Smith
Professor Sam Wilson
Dr Suzannah Rihn
Dr Tetsuo Hasegawa
Dr Virginia Pedicord
Professor Yorgo Modis

Collaborations

Global Health Institute (GHI) is new international partnership between CITIID/University of Cambridge, the University of Hong Kong (HKU), and the International Vaccine Institute (IVI) in Seoul.
Cambridge-GSK Translational Immunology Collaboration (CG-TIC) combines University of Cambridge and GSK expertise in human immunology and immune-mediated diseases, AI and clinical development, with access to patient data and samples provided by Cambridge University Hospitals.