Doctoral Training Programme in Medical Research (DTP-MR)

Data Science for Health 

Dr Elias Allara - Public Health and Primary Care

• Preventative opportunities for coronary heart disease in multi-ancestry patients with non-cardiovascular conditions

Professor Sir Simon Baron-Cohen - Psychiatry

• Sex steroid hormone balance and endocrine health in autistic people

Dr Jamie Blundell - Early Cancer Institute

• The dynamics of methylation in healthy ageing and premalignant disease

Dr Xilin Jiang - Public Health and Primary Care

• Mapping phenotypic variance in complex traits to genetic and non-genetic components using molecular data

Dr Samuel Lambert - Cardiovascular Epidemiology Unit / Public Health and Primary Care

• Exploring multimorbidity involving cardiovascular diseases using multi-omics data

Dr Amy Orben - MRC Cognition and Brain Sciences Unit

• Using Generative AI to explore social media's impact on adolescent health

Infections and Immunity 

Dr Andrew Conway Morris - Medicine

• Understanding mechanisms of pulmonary phenotypes in pneumonia

Dr Maria Duque-Correa - Cambridge Stem Cell Institute

• Studying the impact of parasitic worm infections on intestinal stem cell fate and differentiation

Professor Andres Floto - Medicine (HLRI)

• Understanding pathogenic evolution of bacteria

Dr Akhilesh Jha - Medicine

• Exploring Immune Responses in the Human Respiratory Mucosa: From Cells to In-Vivo Models

Dr Stephen Kaptoge - Public Health and Primary Care

• The epidemiology of bacterial infections and their impact on human health

Dr Nicholas Matheson - Medicine

• Proteomic and functional genomic analysis of the host-pandemic virus interaction

Professor Yorgo Modis - Medicine

• Molecular mechanisms of retroelement control by the Human Silencing Hub

Professor Julian Rayner - Cambridge Institute for Medical Research (CIMR)

• Using large-scale genetic screens in human malaria parasites to identify new antimalarial drug targets

Dr Jeanne Salje - Cambridge Institute for Medical Research (CIMR)

• Hiding from your hosts: how a cytoplasmic bacterium has engineered its cell envelope to avoid detection

Professor Sarah Teichmann - Medicine / Cambridge Stem Cell Institute

• In vivo and in vitro T cell development

Professor Mike Weekes - Cambridge Institute for Medical Research (CIMR)

• Identification and characterisation of novel antiviral restriction factors

Professor Matthias Zilbauer - Cambridge Stem Cell Institute

• Using human organoids to unravel epigenetic mechanisms in health and Inflammatory Bowel Diseases

Molecular and Cellular Mechanisms of Disease 

Dr Edward Avezov - Clinical neurosciences / UK Dementia Research institute

• Gaining control of intracellular stages for amyloidogenesis via high-resolution optical biosensing approaches coupled to nanobody-based protein localisation control

Dr Gabriel Balmus - Clinical neurosciences / UK Dementia Research institute

• The role of DNA repair proteins in neurodegeneration and ageing

Professor Miguel Constancia - Obstetrics and Gynaecology

• Novel approaches to understand the mechanisms of insulin resistance in pregnancy

Professor Janet Deane - Cambridge Institute for Medical Research (CIMR)

• The Glycosphingolipid Code: How do altered protein-lipid interactions drive neurodegenerative disease?

Dr Laura Dearden - Institute of Metabolic Science / Clinical Biochemistry

• Does maternal diet during pregnancy advance ageing of nutrient sensing pathways in the offspring brain?

Dr Melissa Gammons - Medical Genetics (CIMR)

• Unravelling the Interaction between Dishevelled and Axin: A Key to Wnt/β-Catenin Signalling in Health and Disease

Dr David Gershlick - Cambridge Institute for Medical Research (CIMR)

• Unveiling the Molecular Dynamics of Adaptor Protein Complex 3: A Multidisciplinary Exploration into Cellular Mechanisms and Disease Implications

Dr Helle Jorgensen - Medicine

• The impact of the microenvironment on atherosclerotic plaque stability

Professor Walid Khaled - Cambridge Stem Cell Institute

• The tipping point: What governs the transition of precancer to cancer?

Professor Elisa Laurenti - Haematology

• Mechanistic study of how specific mutations associated with clonal haematopoiesis impact human haematopoietic stem cell function

Dr Jonathon Nixon-Abell - Cambridge Institute for Medical Research (CIMR)

• Mechanobiology across organelle interaction networks

Professor Susan Ozanne - Institute of Metabolic Science

• The role of placental exosomes as mediators of programming during obese diabetic pregnancies

Professor Sanjay Sinha - Cambridge Stem Cell Institute

• Modelling vascular disease using patient-derived iPSCs

Dr Jelle van den Ameele - Clinical Neurosciences / MRC Mitochondrial Biology Unit

• Neural stem cell – niche interactions in mitochondrial disease

Professor George Vassiliou - Haematology

• Therapeutic vulnerabilities of TET2-mutant clonal haematopoiesis

Professor Antonio Vidal-Puig - Clinical Biochemistry / IMS

• Crosstalk Between MASLD (Metabolically Associated Steatotic Liver Disease) and Heart Failure with Preserved Ejection Fraction (HFpEF)

Neurosciences and Mental Health 

Professor Franklin Aigbirhio - Molecular Imaging Chemistry Laboratory

• Development of quantitative imaging of the glymphatic system by positron emission tomography

Dr Clemence Blouet - Clinical Biochemistry

• Characterising the central representation of protein hunger

Professor Michael Coleman - Clinical Neurosciences

• Identification of novel mechanisms supporting axon survival with therapeutic potential in neurological disorders

Dr Nick Cunniffe - Clinical Neurosciences

• Uncovering the optimum ways to promote and measure remyelination in people living with multiple sclerosis

Professor Karen Ersche - Psychiatry

• Mapping the neural circuitry of habit re-training: a novel approach for behaviour change in Alcohol Use Disorder

Dr Simon Etkind - Public Health and Primary Care

• Relationship between uncertainty tolerance and mental health outcomes in life-threatening illness

François Guérit - MRC Cognition and Brain Sciences Unit

• Measures of the auditory nerve response to electrical stimulation

Mr Adel Helmy - Clinical Neurosciences / Neurosurgery

• Neurosurgical Tissue Sampling in Acute Brain Injury

Dr Joanne Jones - Clinical Neurosciences

• Understanding the biology of Foxp3+ CD8+ regulatory T cells and their potential role in multiple sclerosis

Dr Janin Lautenschlaeger - Cambridge Institute for Medical Research (CIMR)

• Getting the Disordered in Order: Exploring the Role of Intrinsically Disordered Proteins in Synaptic Vesicle Condensation

Dr Mary-Ellen Lynall - Psychiatry

• Discovering new immune biomarkers and treatments for psychiatric disorders by genetic prioritization and immunophenotyping

Professor Tamar Makin - MRC Cognition and Brain Sciences Unit

• Augmenting motor learning during yoga practice

Dr Selena Milicevic Sephton - Clinical Neurosciences

• Development of PET radiotracers for imaging miRNA in the brain

Dr Virginia Newcombe - Medicine

• Understanding the clinical utility of biomarkers after mild traumatic brain injury

Dr Emanuele Osimo - Psychiatry

• Achieving Personalised Medicine in Mental Health through Use of Routine Clinical Patient Data

Dr Mirabel Pelton - Psychiatry

• Autism and suicide prevention

Professor Stefano Pluchino - Clinical Neurosciences

• Exploring radial glia-like cell neurotoxicity in progressive multiple sclerosis

Professor Chris Rodgers - Clinical Neurosciences

• Neural network approaches to correct for motion in 7T MRI scans

Professor James Rudd - Cardiovascular Medicine

• Predicting Recovery in acute Ischaemic Stroke using Machine learning (PRISM)

Professor Mina Ryten - Clinical Neurosciences

• Leveraging long-read RNA-sequencing to identify novel RNA-targeting therapies for human brain diseases

Emmanuel A Stamatakis - Clinical Neurosciences

• Neurobiology of Consciousness

Dr Varun Warrier - Psychiatry

Integrating neuroimaging and genetics to identify drug targets for severe mental illness

Dr Caroline Williams-Gray - Clinical Neurosciences

• Investigating gut-immune interactions in Parkinson’s disease