Professor Janet Deane

Project/study information 

The cell surface is decorated with an array of proteins and lipids that play essential roles in cell signalling. An important class of these lipids are glycosphingolipids (GSLs). Imbalances in GSL levels underlie a range of severe disorders from neurodegeneration to cancer. My lab investigates the molecular mechanisms by which altered sphingolipid metabolism results in devastating neurological disease.