Luca Peruzzotti Jametti

My journey in medicine and neuroscience began in Milan, Italy, where I obtained my MD and completed a residency in Neurology. My passion for research led me to the University of Cambridge, where I completed a PhD in Clinical Neurosciences in 2018, and to several major universities in European cities, including in Zürich, Aarhus, Lund, and Innsbruck, as a visiting scientist. My career has been a rewarding progression from two post-doctoral positions to becoming a Group Leader within the CCMR in 2022 and the Department of Clinical Neurosciences in 2024. I also have the privilege of serving as an Honorary Neurology Consultant at Addenbrooke's Hospital. 

Over the past decade, my work has been dedicated to understanding the intricate relationship between inflammation and diseases of the central nervous system (CNS). I have focused on developing novel therapeutic strategies, including those using cellular therapies and small molecules, to treat conditions like multiple sclerosis, ischemic stroke, and spinal cord injury.  

I am honoured to have received several fellowships and awards, including a Wellcome Trust RT Fellowship in 2015, a Wellcome Trust CRCD Fellowship in 2020, and an MRC Clinician Scientist Fellowship in 2024. My work has been recognized with the 2018 CSAR PhD Student Award for Applied Research, the 2018 Italian Embassy Italy Made Me Award in Life Sciences, the 2020 UK Society for Extracellular Vesicles Young Investigator award, and the 2022 Rita Levi Montalcini award for Multiple Sclerosis research.  

Project/study information

My lab explores cellular metabolism to find new ways to control chronic inflammation and promote regeneration in the central nervous system. Specifically, we are developing interventions that target neuroimmunometabolism to help heal the persistently inflamed CNS.

Recruitment of PhD / Post doctoral students

I am actively seeking motivated PhD and postdoctoral students to join my team. Our projects focus on utilizing multi-disciplinary approaches to understand and manipulate neuroimmunometabolism in the context of CNS diseases. If you have a background in neuroimmunology, cellular metabolism, or a related field and are interested in our work, please reach out to me via email to discuss potential opportunities.