Professor Paul Luzio

I have a PhD in biochemistry and joined the Department of Clinical Biochemistry in 1977.  In 1998 I moved my lab to the Cambridge Institute for Medical Research (CIMR), where I was also Director for ten years until 2012. Since retirement in 2014, I have remained in the CIMR as an emeritus professor with a voluntary research contract. My major research interest has been studying, in both health and disease, membrane traffic to and from lysosomes, which are small membrane bound organelles within cells that are essential for cellular health and metabolism as well as both susceptibility and resistance to infection. 

Project/study information 

My present main project, funded by the MRC, is to study the organelle remodelling and function of lysosomes, focusing on the regulation of acidity and the coordination and mechanisms of fusion and fission events during the lysosome regeneration cycle, when endosomes and lysosomes interact to form endolysosomes, from which lysosomes are reformed. 

Recruitment of PhD / Post doctoral students 

Not recruiting at present.